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How to generate DNA sequences with Evo 2?

2025-09-05 2.1 K

The DNA sequence generation function of Evo 2 is simple but powerful, as described below:

Operational Processes:

  1. Loading Models::from evo2 import Evo2
    model = Evo2('evo2_7b') # 使用7B参数模型
  2. Enter prompts and generate::prompt = ["ACGT"] # 初始DNA序列
    output = model.generate(prompt_seqs=prompt, n_tokens=400, temperature=1.0, top_k=4)
    print(output.sequences[0]) # 输出400个核苷酸序列

Parameter Description:

  • n_tokens: control the length of the generated sequence
  • temperature: Control of randomness (recommended 0.8-1.2)
  • top_k: Limit the sampling range to optimize the quality of results

The generated sequences can be used directly for downstream bioanalysis or as a starting point for further design.

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