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What is the difference between the 4B and 27B parameter versions of the MedGemma model? How should developers choose?

2025-08-21 516
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MedGemma Version Differences Explained

MedGemma offers models in both 4B and 27B sizes, which differ in capabilities and applicability scenarios.

The main difference

comparison term 4B model Model 27B
parameter scale Four billion. 27 billion
computational requirement Low (single GPU operation) High (requires high-end GPU)
performance Applies to basic tasks More powerful for complex tasks
Available forms Pre-training and command fine-tuning versions available Command fine-tuning version only

Selection Guide

  • Select 4B modelThe situation:
  • - Resource-constrained development environment
  • - Less complex healthcare AI applications
  • - Scenarios that require simultaneous processing of text and images
  • Select model 27BThe situation:
  • - High-performance computing resources available
  • - Need to process complex medical texts (e.g., full EHR analysis)
  • - Need for highest precision image analysis

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